The Effect of the Ala16Val Mutation on the Secondary Structure of the Manganese Superoxide Dismutase Mitochondrial Targeting Sequence

• প্রধান লেখক: Matic Broz (Author), Veronika Furlan (Author), Samo Lešnik (Author), Marko Jukič (Author), Urban Bren (Author)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2022-11-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Manganese Superoxide Dismutase (MnSOD) represents a mitochondrial protein that scavenges reactive oxygen species (ROS) responsible for oxidative stress. A known single nucleotide polymorphism (SNP) rs4880 on the SOD2 gene, causing a mutation from alanine to valine (Ala16Val) in the primary structure...