L-NAME causes antinociception by stimulation of the arginine-NO-cGMP pathway
NG-nitro-L-arginine methyl ester (L-NAME) has been used extensively as a paradigmatic inhibitor of NO synthase and has been shown to cause antinociception in several experimental models. We describe here how L-NAME produced a dose-dependent anti-nociceptive effect when injected intraperitoneally in...
Saved in:
Main Authors: | I. D. G. Duarte (Author), S. H. Ferreira (Author) |
---|---|
Format: | Book |
Published: |
Hindawi Limited,
2000-01-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Synergistic interaction and activation of the opioid receptor-NO-cGMP-K+ channel pathway on peripheral antinociception induced by the α-Bisabolol-diclofenac combination
by: Mario I. Ortiz
Published: (2023) -
Protoporphyrin IX Stimulates Melanogenesis, Melanocyte Dendricity, and Melanosome Transport Through the cGMP/PKG Pathway
by: Jinpeng Lv, et al.
Published: (2020) -
Memory Enhancers for Alzheimer's Dementia: Focus on cGMP
by: Ernesto Fedele, et al.
Published: (2021) -
Rhus coriaria L. (Sumac) Evokes Endothelium-Dependent Vasorelaxation of Rat Aorta: Involvement of the cAMP and cGMP Pathways
by: Mohammad A. Anwar, et al.
Published: (2018) -
cGMP-Dependent Protein Kinase Inhibitors in Health and Disease
by: Jens Schlossmann, et al.
Published: (2013)