Development of a High Throughput Screen for the Identification of Inhibitors of Peptidoglycan <i>O-</i>Acetyltransferases, New Potential Antibacterial Targets
The <i>O</i>-acetylation of peptidoglycan occurs in many Gram-negative and most Gram-positive pathogens and this modification to the essential wall polymer controls the lytic activity of the autolysins, particularly the lytic transglycosylases, and inhibits that of the lysozymes of innat...
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Main Authors: | Ashley S. Brott (Author), Carys S. Jones (Author), Anthony J. Clarke (Author) |
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Format: | Book |
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MDPI AG,
2019-05-01T00:00:00Z.
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