Development of a High Throughput Screen for the Identification of Inhibitors of Peptidoglycan <i>O-</i>Acetyltransferases, New Potential Antibacterial Targets

The <i>O</i>-acetylation of peptidoglycan occurs in many Gram-negative and most Gram-positive pathogens and this modification to the essential wall polymer controls the lytic activity of the autolysins, particularly the lytic transglycosylases, and inhibits that of the lysozymes of innat...

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Bibliographic Details
Main Authors: Ashley S. Brott (Author), Carys S. Jones (Author), Anthony J. Clarke (Author)
Format: Book
Published: MDPI AG, 2019-05-01T00:00:00Z.
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