A snapshot on the on-label and off-label use of the interleukin-1 inhibitors in Italy among rheumatologists and pediatric rheumatologists: a nationwide multi-center retrospective observational study

• Main Authors: Antonio Vitale (Author), Antonella Insalaco (Author), Paolo Sfriso (Author), Giuseppe Lopalco (Author), Giacomo Emmi (Author), Marco Cattalini (Author), Raffaele Manna (Author), Rolando Cimaz (Author), Roberta Priori (Author), Rosaria Talarico (Author), Stefano Gentileschi (Author), Ginevra de Marchi (Author), Micol Frassi (Author), Romina Gallizzi (Author), Alessandra Soriano (Author), Maria Alessio (Author), Daniele Cammelli (Author), Maria Cristina Maggio (Author), Renzo Marcolongo (Author), Francesco La Torre (Author), Claudia Fabiani (Author), Serena Colafrancesco (Author), Francesca Ricci (Author), Paola Galozzi (Author), Ombretta Viapiana (Author), Elena Verrecchia (Author), Manuela Pardeo (Author), Lucia Cerrito (Author), Elena Cavallaro (Author), Alma Nunzia Olivieri (Author), Giuseppe Paolazzi (Author), Gianfranco Vitiello (Author), Armin Maier (Author), Elena Silvestri (Author), Chiara Stagnaro (Author), Guido Valesini (Author), Marta Mosca (Author), Salvatore de Vita (Author), Angela Tincani (Author), Giovanni Lapadula (Author), Bruno Frediani (Author), Fabrizio De Benedetti (Author), Florenzo Iannone (Author), Leonardo Punzi (Author), Carlo Salvarani (Author), Mauro Galeazzi (Author), Donato Rigante (Author), Luca Cantarini (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: interleukin (IL)-1 inhibitors have been suggested as possible therapeutic options in a large number of old and new clinical entities characterized by an IL-1 driven pathogenesis. Objectives: to perform a nationwide snapshot of the on-label and off-label use of anakinra (ANA) and canakinu...