Pharmacokinetic Drug Interaction between Tofacitinib and Voriconazole in Rats
Fungal infections are prevalent in patients with immune diseases. Voriconazole, a triazole antifungal drug, inhibits the cytochromes CYP3A4 and CYP2C, and tofacitinib, a Janus kinase inhibitor for the treatment of rheumatoid arthritis, is metabolized by CYP3A4 and CYP2C19 in humans. Here, we investi...
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| Main Authors: | , , , , |
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| Format: | Book |
| Published: |
MDPI AG,
2021-05-01T00:00:00Z.
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