Cover Image

Albendazole increases the inflammatory response and the amount of Em2-positive small particles of Echinococcus multilocularis (spems) in human hepatic alveolar echinococcosis lesions.

Alveolar echinococcosis (AE) is caused by the metacestode stage of Echinococcus multilocularis. The inflammatory response to this infection is influenced by the interaction of the parasite with the host. We aimed to analyze human liver lesions infected with Echinococcus multilocularis and the change...

Full description

Saved in:

Bibliographic Details
Main Authors:	Franz J Ricken (Author), Juliane Nell (Author), Beate Grüner (Author), Julian Schmidberger (Author), Tanja Kaltenbach (Author), Wolfgang Kratzer (Author), Andreas Hillenbrand (Author), Doris Henne-Bruns (Author), Peter Deplazes (Author), Peter Moller (Author), Peter Kern (Author), Thomas F E Barth (Author)
Format:	Book
Published:	Public Library of Science (PLoS), 2017-05-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Immunohistological detection of small particles of Echinococcus multilocularis and Echinococcus granulosus in lymph nodes is associated with enlarged lymph nodes in alveolar and cystic echinococcosis.
by: Johannes Grimm, et al.
Published: (2020)

Survey of public knowledge about <it>Echinococcus multilocularis </it>in four European countries: Need for proactive information
by: Romig Thomas, et al.
Published: (2008)

Echinococcus multilocularis specific antibody, systemic cytokine, and chemokine levels, as well as antigen-specific cellular responses in patients with progressive, stable, and cured alveolar echinococcosis: A 10-year follow-up.
by: Beate Grüner, et al.
Published: (2022)

Dynamics of the force of infection: insights from Echinococcus multilocularis infection in foxes.
by: Fraser I Lewis, et al.
Published: (2014)

Establishing and evaluation of a polymerase chain reaction for the detection of Echinococcus multilocularis in human tissue.
by: Johannes Grimm, et al.
Published: (2021)

Genetic diversity of Echinococcus multilocularis and Echinococcus granulosus sensu lato in Kyrgyzstan: The A2 haplotype of E. multilocularis is the predominant variant infecting humans.
by: Cristian A Alvarez Rojas, et al.
Published: (2020)

Sensitive and specific immunohistochemical diagnosis of human alveolar echinococcosis with the monoclonal antibody Em2G11.
by: Thomas F E Barth, et al.
Published: (2012)

Human alveolar echinococcosis in Slovakia: Epidemiology and genetic diversity of Echinococcus multilocularis, 2000-2023.
by: Daniela Antolová, et al.
Published: (2024)

Albendazole reduces hepatic inflammation and endoplasmic reticulum-stress in a mouse model of chronic Echinococcus multilocularis infection.
by: Michael Weingartner, et al.
Published: (2022)

Genetic diversity of the cestode Echinococcus multilocularis in red foxes at a continental scale in Europe.
by: Jenny Knapp, et al.
Published: (2009)

Targeting Echinococcus multilocularis PIM kinase for improving anti-parasitic chemotherapy.
by: Akito Koike, et al.
Published: (2022)

A multiplex PCR for differential detection of Echinococcus granulosus sensu stricto, Echinococcus multilocularis and Echinococcus canadensis in China
by: Jing-Ye Shang, et al.
Published: (2019)

Impairing the maintenance of germinative cells in Echinococcus multilocularis by targeting Aurora kinase.
by: Zhe Cheng, et al.
Published: (2019)

Extracellular non-coding RNA signatures of the metacestode stage of Echinococcus multilocularis.
by: María Eugenia Ancarola, et al.
Published: (2020)

Drivers of Echinococcus multilocularis transmission in China: small mammal diversity, landscape or climate?
by: Patrick Giraudoux, et al.
Published: (2013)

Three-dimensional hepatocyte culture system for the study of Echinococcus multilocularis larval development.
by: Li Li, et al.
Published: (2018)

Molecular identification of Echinococcus multilocularis infection in small mammals from Northeast, Iran.
by: Molouk Beiromvand, et al.
Published: (2013)

Expression profiling of Echinococcus multilocularis miRNAs throughout metacestode development in vitro.
by: Natalia Macchiaroli, et al.
Published: (2021)

Deciphering the role of miR-71 in Echinococcus multilocularis early development in vitro.
by: Matías Gastón Pérez, et al.
Published: (2019)

Analysis on Gene Expression Profile in Oncospheres and Early Stage Metacestodes from Echinococcus multilocularis.
by: Fuqiang Huang, et al.
Published: (2016)

Detection of Echinococcus multilocularis in carnivores in Razavi Khorasan province, Iran using mitochondrial DNA.
by: Molouk Beiromvand, et al.
Published: (2011)

Lasiopodomys fuscus as an important intermediate host for Echinococcus multilocularis: isolation and phylogenetic identification of the parasite
by: Qi-Gang Cai, et al.
Published: (2018)

The role of fibroblast growth factor signalling in Echinococcus multilocularis development and host-parasite interaction.
by: Sabine Förster, et al.
Published: (2019)

2-Deoxy-D-glucose and combined 2-Deoxy-D-glucose/albendazole exhibit therapeutic efficacy against Echinococcus granulosus protoscoleces and experimental alveolar echinococcosis.
by: Qi Xin, et al.
Published: (2022)

Targeting Echinococcus multilocularis stem cells by inhibition of the Polo-like kinase EmPlk1.
by: Andreas Schubert, et al.
Published: (2014)

Infection of sheep by Echinococcus multilocularis in Gansu, China: evidence from mitochondrial and nuclear DNA analysis
by: Nigus Abebe Shumuye, et al.
Published: (2023)

Transplantation of adipose-derived stem cells ameliorates Echinococcus multilocularis-induced liver fibrosis in mice.
by: Ning Yang, et al.
Published: (2022)

Comparison of local ablation with Albendazole or laparoscopic hepatectomy combined with Albendazole in the treatment of early hepatic alveolar echinococcosis
by: Jide A, et al.
Published: (2022)

Estimating the prevalence of Echinococcus in domestic dogs in highly endemic for echinococcosis
by: Cong-Nuan Liu, et al.
Published: (2018)

Excretory/secretory-products of Echinococcus multilocularis larvae induce apoptosis and tolerogenic properties in dendritic cells in vitro.
by: Justin Komguep Nono, et al.
Published: (2012)

Efficacy of Albendazole-Chitosan Microsphere-based Treatment for Alveolar Echinococcosis in Mice.
by: Maitiseyiti Abulaihaiti, et al.
Published: (2015)

EmTIP, a T-Cell immunomodulatory protein secreted by the tapeworm Echinococcus multilocularis is important for early metacestode development.
by: Justin Komguep Nono, et al.
Published: (2014)

Past and present of cystic echinococcosis in Bolivia.
by: Viterman Ali, et al.
Published: (2021)

Correction: Efficacy of Albendazole-Chitosan Microsphere-based Treatment for Alveolar Echinococcosis in Mice.
by: PLOS Neglected Tropical Diseases Staff
Published: (2015)

A MEKK1 - JNK mitogen activated kinase (MAPK) cascade module is active in Echinococcus multilocularis stem cells.
by: Kristin Stoll, et al.
Published: (2021)

Mucosal adjuvanticity of fibronectin-binding peptide (FBP) fused with Echinococcus multilocularis tetraspanin 3: systemic and local antibody responses.
by: Zhisheng Dang, et al.
Published: (2012)

Understanding pathogen-host interplay by expression profiles of lncRNA and mRNA in the liver of Echinococcus multilocularis-infected mice.
by: Xiaofeng Nian, et al.
Published: (2022)

Regulation of hepatic microRNAs in response to early stage Echinococcus multilocularis egg infection in C57BL/6 mice.
by: Ghalia Boubaker, et al.
Published: (2020)

EGF-mediated EGFR/ERK signaling pathway promotes germinative cell proliferation in Echinococcus multilocularis that contributes to larval growth and development.
by: Zhe Cheng, et al.
Published: (2017)

Profound activity of the anti-cancer drug bortezomib against Echinococcus multilocularis metacestodes identifies the proteasome as a novel drug target for cestodes.
by: Britta Stadelmann, et al.
Published: (2014)