Lamotrigine hypersensitivity syndrome and spiking fever

We report a case of a 26 year old woman with rash, lymphadenopathy, liver enzyme abnormalities and spiking fever. She was diagnosed with drug-induced hypersensitivity syndrome (DHS) to lamotrigine. Spiking fever in relation to drug-induced hypersensitivity syndrome has not earlier been described in...

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Bibliographic Details
Main Authors: Christiaan V Bakker (Author), Vincent Noordhoek Hegt (Author), Marinus C G Van Praag (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2012-01-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Christiaan V Bakker  |e author 
700 1 0 |a Vincent Noordhoek Hegt  |e author 
700 1 0 |a Marinus C G Van Praag  |e author 
245 0 0 |a Lamotrigine hypersensitivity syndrome and spiking fever 
260 |b Wolters Kluwer Medknow Publications,   |c 2012-01-01T00:00:00Z. 
500 |a 0019-5154 
500 |a 1998-3611 
500 |a 10.4103/0019-5154.103087 
520 |a We report a case of a 26 year old woman with rash, lymphadenopathy, liver enzyme abnormalities and spiking fever. She was diagnosed with drug-induced hypersensitivity syndrome (DHS) to lamotrigine. Spiking fever in relation to drug-induced hypersensitivity syndrome has not earlier been described in adults. Spiking fever is an important symptom of the wide spectrum of disease presentation. The syndrome is commonly referred to as either Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) or DHS. In accord with previous authors we see both syndromes as two ends of a spectrum, with a wide range of symptoms and presentations. Therefore we plea for unity in nomenclature. 
546 |a EN 
690 |a DRESS 
690 |a hypersensitivity syndrome 
690 |a lamotrigine 
690 |a spiking fever 
690 |a Dermatology 
690 |a RL1-803 
655 7 |a article  |2 local 
786 0 |n Indian Journal of Dermatology, Vol 57, Iss 6, Pp 504-504 (2012) 
787 0 |n http://www.e-ijd.org/article.asp?issn=0019-5154;year=2012;volume=57;issue=6;spage=504;epage=504;aulast=Bakker 
787 0 |n https://doaj.org/toc/0019-5154 
787 0 |n https://doaj.org/toc/1998-3611 
856 4 1 |u https://doaj.org/article/cd9c418e882c4f01a816baa74dcebf57  |z Connect to this object online.