In Vitro Predictive Model for Intestinal Lymphatic Uptake: Exploration of Additional Enhancers and Inhibitors

• Main Authors: Malaz Yousef (Author), Conor O'Croinin (Author), Tyson S. Le (Author), Chulhun Park (Author), Jieyu Zuo (Author), Nadia Bou Chacra (Author), Neal M. Davies (Author), Raimar Löbenberg (Author)
• Format: Book
• Published: MDPI AG, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Drug absorption via chylomicrons holds significant implications for both pharmacokinetics and pharmacodynamics. However, a mechanistic understanding of predicting in vivo intestinal lymphatic uptake remains largely unexplored. This study aimed to delve into the intestinal lymphatic uptake of drugs,...