Braf protein mutation and its significancy within patients with melanoma

Introduction and purpose:   This review aims to analyze BRAF mutation significancy and its influence on progression and therapy methods within patients with melanoma.  Material and method:  This review was mainly based on articles collected in Pubmed in years 2004-2018. The research was done by look...

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Main Authors: Julia Kuchnicka (Author), Aleksandra Kuchnicka (Author), Katarzyna Kosz (Author), Klaudia Remjasz (Author), Natalia Zarankiewicz (Author), Martyna Zielińska (Author), Klaudia Sapuła (Author), Jakub Aleksandrowicz (Author), Wojciech Siedlecki (Author)
Format: Book
Published: Kazimierz Wielki University, 2022-08-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Julia Kuchnicka  |e author 
700 1 0 |a Aleksandra Kuchnicka  |e author 
700 1 0 |a Katarzyna Kosz  |e author 
700 1 0 |a Klaudia Remjasz  |e author 
700 1 0 |a Natalia Zarankiewicz  |e author 
700 1 0 |a Martyna Zielińska  |e author 
700 1 0 |a Klaudia Sapuła  |e author 
700 1 0 |a Jakub Aleksandrowicz  |e author 
700 1 0 |a Wojciech Siedlecki  |e author 
245 0 0 |a Braf protein mutation and its significancy within patients with melanoma 
260 |b Kazimierz Wielki University,   |c 2022-08-01T00:00:00Z. 
500 |a 10.12775/JEHS.2022.12.08.076 
500 |a 2391-8306 
520 |a Introduction and purpose:   This review aims to analyze BRAF mutation significancy and its influence on progression and therapy methods within patients with melanoma.  Material and method:  This review was mainly based on articles collected in Pubmed in years 2004-2018. The research was done by looking through keywords as follows "braf kinase", "braf mutation", "melanoma" "wemurafenib".  Results:  The selected studies have demonstrated that it is justified to identify patient with BRAF mutation due to it's influence on treatment's method choosing.  Conclusions:  Citied researches have proven BRAF mutation significancy in growth and progressions of many malignant tumors. Further tests are likely to not only prolong life expectancy within patients with melanoma, but also being a source of crucial knowledge about tumors development.  
546 |a EN 
546 |a ES 
546 |a PL 
546 |a RU 
546 |a UK 
690 |a braf kinase 
690 |a braf mutation 
690 |a melanoma 
690 |a wemurafenib 
690 |a Education 
690 |a L 
690 |a Sports 
690 |a GV557-1198.995 
690 |a Medicine 
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655 7 |a article  |2 local 
786 0 |n Journal of Education, Health and Sport, Vol 12, Iss 8 (2022) 
787 0 |n https://apcz.umk.pl/JEHS/article/view/39472 
787 0 |n https://doaj.org/toc/2391-8306 
856 4 1 |u https://doaj.org/article/cdb606c1d8ef4d26b45b4c8b9a231444  |z Connect to this object online.