Histone deacetylase inhibitors modulate KATP subunit transcription in HL-1 cardiomyocytes through effects on cholesterol homeostasis

• Main Authors: Naheed eFatima (Author), Devin C Cohen (Author), Gauthaman eSukumar (Author), Tristan M Sissung (Author), James F Schooley (Author), Mark C Haigney (Author), William C Claycomb (Author), Rachel T Cox (Author), Clifton Lee Dalgard (Author), Susan E. Bates (Author), Thomas P Flagg (Author)
• Format: Book
• Published: Frontiers Media S.A., 2015-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Histone deacetylase inhibitors (HDIs) are under investigation for the treatment of a number of human health problems. HDIs have proven therapeutic value in refractory cases of cutaneous T-cell lymphoma,. Electrocardiographic ST segment morphological changes associated with HDIs were observed during...