Estimation of serum cortisol levels in oral lichen planus patients with electrochemiluminescence

Objectives: The objectives of this study were to compare the serum cortisol level in oral lichen planus (OLP) patients with normal healthy individuals and to compare the serum cortisol level in patients with erosive and nonerosive forms of OLP. Materials and Methods: A case-control study involving 6...

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Main Authors: Sam Jose (Author), Jayasree Vijayalakshmi Mukundan (Author), Joseph Johny (Author), Arun Tom (Author), Sunil Paramel Mohan (Author), Anjali Sreenivasan (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2019-01-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Sam Jose  |e author 
700 1 0 |a Jayasree Vijayalakshmi Mukundan  |e author 
700 1 0 |a Joseph Johny  |e author 
700 1 0 |a Arun Tom  |e author 
700 1 0 |a Sunil Paramel Mohan  |e author 
700 1 0 |a Anjali Sreenivasan  |e author 
245 0 0 |a Estimation of serum cortisol levels in oral lichen planus patients with electrochemiluminescence 
260 |b Wolters Kluwer Medknow Publications,   |c 2019-01-01T00:00:00Z. 
500 |a 0975-7406 
500 |a 10.4103/JPBS.JPBS_7_19 
520 |a Objectives: The objectives of this study were to compare the serum cortisol level in oral lichen planus (OLP) patients with normal healthy individuals and to compare the serum cortisol level in patients with erosive and nonerosive forms of OLP. Materials and Methods: A case-control study involving 60 patients within the age group of 20-50 years was carried out. Group A included 15 subjects with nonerosive lichen planus, without skin involvement; Group B included 15 subjects with erosive lichen planus, without skin; and Group C included 30 subjects with no apparent lesions of the oral mucosa and the skin. From the cases and controls, 7mL venous blood was taken from median cubital vein two times (between 8 and 10 am, and 4 and 6 pm) by using a 10mL syringe from which 5mL was taken for estimation of serum cortisol. Results: The serum cortisol levels of the erosive OLP patients were significantly higher than those of nonerosive OLP patients and controls. There was no significant difference in the serum cortisol levels between nonerosive OLP in comparison with controls. 
546 |a EN 
690 |a Cortisol 
690 |a erosive 
690 |a lichen planus 
690 |a Pharmacy and materia medica 
690 |a RS1-441 
690 |a Analytical chemistry 
690 |a QD71-142 
655 7 |a article  |2 local 
786 0 |n Journal of Pharmacy and Bioallied Sciences, Vol 11, Iss 6, Pp 265-268 (2019) 
787 0 |n http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2019;volume=11;issue=6;spage=265;epage=268;aulast=Jose 
787 0 |n https://doaj.org/toc/0975-7406 
856 4 1 |u https://doaj.org/article/cde02ac6e31d4aa288522cbc144882eb  |z Connect to this object online.