Association of the rs738409 polymorphism in <it>PNPLA3 </it>with liver damage and the development of nonalcoholic fatty liver disease

• Main Authors: Chayama Kazuaki (Author), Mizusawa Seiho (Author), Ueno Takato (Author), Ochi Hidenori (Author), Hyogo Hideyuki (Author), Yoneda Masato (Author), Hotta Kikuko (Author), Nakajima Atsushi (Author), Nakao Kazuwa (Author), Sekine Akihiro (Author)
• Format: Book
• Published: BMC, 2010-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>In a genome-wide association scan, the single-nucleotide polymorphism (SNP) rs738409 in the patatin-like phospholipase 3 gene (<it>PNPLA3</it>) was strongly associated with increased liver fat content. We investigated whe...