In Vivo Predictive Dissolution (IPD) for Carbamazepine Formulations: Additional Evidence Regarding a Biopredictive Dissolution Medium

• Main Authors: Marival Bermejo (Author), Jessica Meulman (Author), Marcelo Gomes Davanço (Author), Patricia de Oliveira Carvalho (Author), Isabel Gonzalez-Alvarez (Author), Daniel Rossi Campos (Author)
• Format: Book
• Published: MDPI AG, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aim of the present study was to bring additional evidence regarding a biopredictive dissolution medium containing 1% sodium lauryl sulphate (SLS) to predict the in vivo behavior of carbamazepine (CBZ) products. Twelve healthy volunteers took one immediate release (IR) dose of either test and ref...