STUDYING DOSE-DEPENDENT ENDOTHELIO- AND CARDIOPROTECTIVE ACTIVITY OF SELECTIVE ARGINASE II INHIBITOR IN HYPERHOMOCYSTEINE-INDUCED ENDOTHELIAL DYSFUNCTION
This paper deals with the study of endothelio- and cardioprotective activity of arginase II selective inhibitor, the substance under the code ZB49-0010C in the model of hyperhomocysteine-induced endothelial dysfunction. The results of the studies prove the presence in the arginase II selective inhib...
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| Format: | Book |
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Belgorod National Research University,
2016-03-01T00:00:00Z.
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| 001 | doaj_ce3c5721c83b4e4e92d1948235e32a7c | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Vladimir Yakushev |e author |
| 700 | 1 | 0 | |a Nikolaj Filippenko |e author |
| 700 | 1 | 0 | |a Irina Kizilova |e author |
| 700 | 1 | 0 | |a Mikhail Korokin |e author |
| 700 | 1 | 0 | |a Evgeniya Beskhmelnitsyna |e author |
| 700 | 1 | 0 | |a Anna Litvinova |e author |
| 245 | 0 | 0 | |a STUDYING DOSE-DEPENDENT ENDOTHELIO- AND CARDIOPROTECTIVE ACTIVITY OF SELECTIVE ARGINASE II INHIBITOR IN HYPERHOMOCYSTEINE-INDUCED ENDOTHELIAL DYSFUNCTION |
| 260 | |b Belgorod National Research University, |c 2016-03-01T00:00:00Z. | ||
| 500 | |a 10.18413/2313-8971-2016-2-1-42-45 | ||
| 500 | |a 2658-381X | ||
| 520 | |a This paper deals with the study of endothelio- and cardioprotective activity of arginase II selective inhibitor, the substance under the code ZB49-0010C in the model of hyperhomocysteine-induced endothelial dysfunction. The results of the studies prove the presence in the arginase II selective inhibitor, the substance under the code ZB49-0010C, dosedependent endothelioprotective and cardioprotective activity, which expression increases with the increase in dose and is maximum at a dose of 10 mg/kg. The research was partially supported by the grant of the President of the Russian Federation №MD-4711.2015.7. | ||
| 546 | |a EN | ||
| 690 | |a endothelial dysfunction | ||
| 690 | |a a selective inhibitor of | ||
| 690 | |a Therapeutics. Pharmacology | ||
| 690 | |a RM1-950 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Research Results in Pharmacology, Vol 2, Iss 1, Pp 42-45 (2016) | |
| 787 | 0 | |n https://rrpharmacology.pensoft.net/article/31039/download/pdf/ | |
| 787 | 0 | |n https://rrpharmacology.pensoft.net/article/31039/download/xml/ | |
| 787 | 0 | |n https://rrpharmacology.pensoft.net/article/31039/ | |
| 787 | 0 | |n https://doaj.org/toc/2658-381X | |
| 856 | 4 | 1 | |u https://doaj.org/article/ce3c5721c83b4e4e92d1948235e32a7c |z Connect to this object online. |