Functions and mechanisms of lncRNA MALAT1 in cancer chemotherapy resistance

Abstract Chemotherapy is one of the most important treatments for cancer therapy. However, chemotherapy resistance is a big challenge in cancer treatment. Due to chemotherapy resistance, drugs become less effective or no longer effective at all. In recent years, long non-coding RNA metastasis-associ...

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Main Authors: Junhui Hou (Author), Gong Zhang (Author), Xia Wang (Author), Yuan Wang (Author), Kefeng Wang (Author)
Format: Book
Published: BMC, 2023-02-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Junhui Hou  |e author 
700 1 0 |a Gong Zhang  |e author 
700 1 0 |a Xia Wang  |e author 
700 1 0 |a Yuan Wang  |e author 
700 1 0 |a Kefeng Wang  |e author 
245 0 0 |a Functions and mechanisms of lncRNA MALAT1 in cancer chemotherapy resistance 
260 |b BMC,   |c 2023-02-01T00:00:00Z. 
500 |a 10.1186/s40364-023-00467-8 
500 |a 2050-7771 
520 |a Abstract Chemotherapy is one of the most important treatments for cancer therapy. However, chemotherapy resistance is a big challenge in cancer treatment. Due to chemotherapy resistance, drugs become less effective or no longer effective at all. In recent years, long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) has been found to be associated with the development of chemotherapy resistance, suggesting that MALAT1 may be an important target to overcome chemotherapy resistance. In this review, we introduced the main mechanisms of chemotherapy resistance associated with MALAT1, which may provide new approaches for cancer treatment. 
546 |a EN 
690 |a Long non-coding RNA 
690 |a MALAT1 
690 |a Chemotherapy resistance 
690 |a Cancer 
690 |a Treatment 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
655 7 |a article  |2 local 
786 0 |n Biomarker Research, Vol 11, Iss 1, Pp 1-11 (2023) 
787 0 |n https://doi.org/10.1186/s40364-023-00467-8 
787 0 |n https://doaj.org/toc/2050-7771 
856 4 1 |u https://doaj.org/article/ce49b8ec414e44b6ba30e976c8d8dc97  |z Connect to this object online.