The potential molecularly therapy target to MYCN‐amplificated neuroblastoma

• Main Authors: Susu Jiang (Author), Xinxin Zhang (Author), Jiaming Chang (Author), Jinhong Zhu (Author), Wenhan Yang (Author), Jing He (Author)
• Format: Book
• Published: Wiley, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Neuroblastoma (NB) is an embryonal deadly cancer in childhood driven by MYC or MYCN‐driven oncogenic signaling. The amplification of MYCN leads to malignant progression of NB and poor prognosis. Traditional chemotherapy is still a standard treatment for NB. Most of the cytostatic drugs take...