A Novel Flow Cytometry-Based Assay for the Identification of HCN4 CNBD Ligands

Hyperpolarization-activated and cyclic nucleotide-gated (HCN) channels are promising therapeutic targets because of their association with the genesis of several diseases. The identification of selective compounds that alter cAMP-induced ion channel modulation by binding to the cyclic nucleotide-bin...

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Main Authors: Magdalena N. Wojciechowski (Author), Sebastian Schreiber (Author), Joachim Jose (Author)
Format: Knjiga
Izdano: MDPI AG, 2023-05-01T00:00:00Z.
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