A Novel Flow Cytometry-Based Assay for the Identification of HCN4 CNBD Ligands

• Główni autorzy: Magdalena N. Wojciechowski (Autor), Sebastian Schreiber (Autor), Joachim Jose (Autor)
• Format: Książka
• Wydane: MDPI AG, 2023-05-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Hyperpolarization-activated and cyclic nucleotide-gated (HCN) channels are promising therapeutic targets because of their association with the genesis of several diseases. The identification of selective compounds that alter cAMP-induced ion channel modulation by binding to the cyclic nucleotide-bin...