Conservative Non-intervention Approach for Hemodynamically Significant Patent Ductus Arteriosus in Extremely Preterm Infants

While persistent patent ductus arteriosus (PDA) in preterm infants has been known to be associated with increased mortality and morbidities including bronchopulmonary dysplasia, and necrotizing enterocolitis, there is minimal evidence supporting their causal relationships, and most traditional medic...

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Main Authors: Se In Sung (Author), Yun Sil Chang (Author), So Yoon Ahn (Author), Heui Seung Jo (Author), Misun Yang (Author), Won Soon Park (Author)
Format: Book
Published: Frontiers Media S.A., 2020-12-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Se In Sung  |e author 
700 1 0 |a Yun Sil Chang  |e author 
700 1 0 |a So Yoon Ahn  |e author 
700 1 0 |a Heui Seung Jo  |e author 
700 1 0 |a Misun Yang  |e author 
700 1 0 |a Won Soon Park  |e author 
245 0 0 |a Conservative Non-intervention Approach for Hemodynamically Significant Patent Ductus Arteriosus in Extremely Preterm Infants 
260 |b Frontiers Media S.A.,   |c 2020-12-01T00:00:00Z. 
500 |a 2296-2360 
500 |a 10.3389/fped.2020.605134 
520 |a While persistent patent ductus arteriosus (PDA) in preterm infants has been known to be associated with increased mortality and morbidities including bronchopulmonary dysplasia, and necrotizing enterocolitis, there is minimal evidence supporting their causal relationships, and most traditional medical and/or surgical treatments have failed to show improvements in these outcomes. As such, the pendulum has swung toward the conservative non-intervention approach for the management of persistent PDA during the last decade; however, the benefits and risks of this approach are unclear. In this mini review, we focused on whom, when, and how to apply the conservative non-intervention approach for persistent PDA, especially in extremely preterm infants. 
546 |a EN 
690 |a patent ductus arteriosus 
690 |a premature infants 
690 |a extremely preterm infants 
690 |a conservative management 
690 |a non-intervention 
690 |a Pediatrics 
690 |a RJ1-570 
655 7 |a article  |2 local 
786 0 |n Frontiers in Pediatrics, Vol 8 (2020) 
787 0 |n https://www.frontiersin.org/articles/10.3389/fped.2020.605134/full 
787 0 |n https://doaj.org/toc/2296-2360 
856 4 1 |u https://doaj.org/article/cf22b0ef756f4fb6a3d5096bc0d61b91  |z Connect to this object online.