Conservative Treatment of Bisphosphonate-Related Osteonecrosis of the Jaw in Multiple Myeloma Patients

• Main Authors: Pelagia I. Melea (Author), Ioannis Melakopoulos (Author), Efstathios Kastritis (Author), Christina Tesseromatis (Author), Vasileios Margaritis (Author), Meletios A. Dimopoulos (Author), Evangelos Terpos (Author)
• Format: Book
• Published: Hindawi Limited, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The use of intravenous bisphosphonates (pamidronate or zoledronic acid) is the cornerstone for the management of multiple myeloma-(MM-) related bone disease. However, osteonecrosis of the jaw (ONJ) is a rare, but sometimes difficult to manage, adverse effect of bisphosphonates therapy. A retrospecti...