Neonatal Gastric Lactobezoar: Management with N-Acetylcysteine

Gastric lactobezoars (GLBs) are the most common form of bezoars in neonates and consist of aggregations of undigested milk constituents. GLB can present with a variety of intra-abdominal clinical symptoms, and occasionally, extra-abdominal symptoms. Conservative management, with a period of bowel re...

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Bibliographic Details
Main Authors: Sarah Bajorek (Author), Roel Basaldua (Author), Katherine McGoogan (Author), Charla Miller (Author), Craig B. Sussman (Author)
Format: Book
Published: Hindawi Limited, 2012-01-01T00:00:00Z.
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Summary:Gastric lactobezoars (GLBs) are the most common form of bezoars in neonates and consist of aggregations of undigested milk constituents. GLB can present with a variety of intra-abdominal clinical symptoms, and occasionally, extra-abdominal symptoms. Conservative management, with a period of bowel rest and intravenous fluids, is the most common treatment regimen for uncomplicated GLB. Surgical measures are reserved for the rare complications of obstruction and/or perforation. Although limited, utilization of the protein-cleaving enzyme N-acetylcysteine has been described for the disintegration of GLB in toddlers. In this paper, we discuss the first documented use of N-acetylcysteine for a neonatal GLB. Supporting literature, the infant's unusual presentation, and details of the treatment regimen are discussed.
Item Description:2090-6803
2090-6811
10.1155/2012/412412