Sitagliptin Accelerates Endothelial Regeneration after Vascular Injury Independent from GLP1 Receptor Signaling

• প্রধান লেখক: Friederike Remm (Author), Nicolle Kränkel (Author), Daniela Lener (Author), Daniel J. Drucker (Author), Sieghart Sopper (Author), Christoph Brenner (Author)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Hindawi Limited, 2018-01-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Introduction. DPP4 inhibitors (gliptins) are commonly used antidiabetic drugs for the treatment of type 2 diabetes. Gliptins also act in a glucose-independent manner and show vasoregenerative effects. We have shown that gliptins can remarkably accelerate vascular healing after vascular injury. Howev...