Effect of cough technique and cryogen gas on temperatures achieved during simulated cryotherapy
<p>Abstract</p> <p>Background</p> <p>Cryotherapy is often used to treat cervical precancer in developing countries. There are different methods and cryogen gases used for cryotherapy, including the freeze-flush-freeze (cough) technique employed to minimize gas blockage....
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| Main Authors: | , , , , |
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| Format: | Book |
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BMC,
2007-10-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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| Summary: | <p>Abstract</p> <p>Background</p> <p>Cryotherapy is often used to treat cervical precancer in developing countries. There are different methods and cryogen gases used for cryotherapy, including the freeze-flush-freeze (cough) technique employed to minimize gas blockage. However, there is limited information to compare their effectiveness.</p> <p>Methods</p> <p>Using a tissue model, we compared temperature-time curves for four cryotherapy methods: uninterrupted freezing with nitrous oxide (N<sub>2</sub>O) and carbon dioxide (CO<sub>2</sub>), and two methods using a standard and extended version of the cough technique with CO<sub>2</sub>.</p> <p>Results</p> <p>Uninterrupted freezing with both N<sub>2</sub>O and CO<sub>2 </sub>produced tissue temperatures less than -20°C (-40°C and -30°C respectively). CO<sub>2 </sub>cryotherapy procedures using the two cough techniques produced temperatures greater than -20°C in the model tissue.</p> <p>Conclusion</p> <p>CO<sub>2 </sub>cryotherapy using the cough technique may not achieve sufficiently low temperatures to produce the desired therapeutic effect. Other alternatives to the prevention of gas blockage should be developed.</p> |
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| Item Description: | 10.1186/1472-6874-7-16 1472-6874 |