GdCl3 attenuates the glomerular sclerosis of streptozotocin (STZ) induced diabetic rats via inhibiting TGF-β/Smads signal pathway

• Autori principali: Jialin Li (Autore), Bing Wu (Autore), Haibo Hu (Autore), Xiansong Fang (Autore), Zhiping Liu (Autore), Suzhen Wu (Autore)
• Natura: Libro
• Pubblicazione: Elsevier, 2020-02-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Diabetic nephropathy (DN) is the most serious end-stage renal disease which characterized by renal glomerular sclerosis including glomerular hypertrophy, glomerular basement membrane (GBM) thickening, mesangial expansion and renal fibrosis. TGF-β/Smads signal pathway plays a crucial role in the deve...