Ferroptosis induces nucleolar stress as revealed by live-cell imaging using thioflavin T

• Autori principali: Yoko Hirata (Autore), Hiroshi Takemori (Autore), Kyoji Furuta (Autore), Yuji O. Kamatari (Autore), Makoto Sawada (Autore)
• Natura: Libro
• Pubblicazione: Elsevier, 2024-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Nucleolar stress induced by stressors like hypoxia, UV irradiation, and heat shock downregulates ribosomal RNA transcription, thereby impairing protein synthesis capacity and potentially contributing to cell senescence and various human diseases such as neurodegenerative disorders and cancer. Live-c...