Drug Resistant Hypertension - No SIMPLE Way Out

Hypertension poses growing challenge for health policy-makers and doctors worldwide. Recently published results of Symplicity-III trial (HTN-3), the first blinded, randomized, multicenter study on the efficacy of renal denervation for the treatment of resistant hypertension did not show a significan...

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Bibliographic Details
Main Authors: Janusz Skrzypecki (Author), Marcin Ufnal (Author)
Format: Book
Published: Karger Publishers, 2015-02-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Janusz Skrzypecki  |e author 
700 1 0 |a Marcin Ufnal  |e author 
245 0 0 |a Drug Resistant Hypertension - No SIMPLE Way Out 
260 |b Karger Publishers,   |c 2015-02-01T00:00:00Z. 
500 |a 1420-4096 
500 |a 1423-0143 
500 |a 10.1159/000368483 
520 |a Hypertension poses growing challenge for health policy-makers and doctors worldwide. Recently published results of Symplicity-III trial (HTN-3), the first blinded, randomized, multicenter study on the efficacy of renal denervation for the treatment of resistant hypertension did not show a significant reduction of BP in patients with resistant hypertension 6 months after renal-artery denervation, as compared with controls. In this paper we review clinical and experimental studies on renal denervation. In order to identify causes of inconsistent results in renal denervation studies we look at basic science support for renal denervation and at designs of clinical trials. 
546 |a EN 
690 |a Hypertension 
690 |a Renal denervation 
690 |a Blood pressure 
690 |a Heart failure 
690 |a Chronic kidney disease 
690 |a Sleep apnea syndrome 
690 |a Metabolic syndrome 
690 |a Dermatology 
690 |a RL1-803 
690 |a Diseases of the circulatory (Cardiovascular) system 
690 |a RC666-701 
690 |a Diseases of the genitourinary system. Urology 
690 |a RC870-923 
655 7 |a article  |2 local 
786 0 |n Kidney & Blood Pressure Research, Vol 40, Iss 1, Pp 66-76 (2015) 
787 0 |n http://www.karger.com/Article/FullText/368483 
787 0 |n https://doaj.org/toc/1420-4096 
787 0 |n https://doaj.org/toc/1423-0143 
856 4 1 |u https://doaj.org/article/cfdfe3fdff8f46f39885e9769824ab72  |z Connect to this object online.