Icariin, but Not Genistein, Exerts Osteogenic and Anti-apoptotic Effects in Osteoblastic Cells by Selective Activation of Non-genomic ERα Signaling

• Principais autores: Ming-Xian Ho (Autor), Christina C.-W. Poon (Autor), Ka-Chun Wong (Autor), Zuo-Cheng Qiu (Autor), Man-Sau Wong (Autor)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2018-05-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Genistein and icariin are flavonoid compounds that exhibit estrogen-like properties in inducing bone formation and reducing bone loss associated with estrogen deficiency in both preclinical and clinical studies. However, the mechanisms that are involved in mediating their estrogenic actions in bone...