Model‐based meta‐analysis of non‐small cell lung cancer with standard of care PD‐1 inhibitors and chemotherapy for early development decision making

• Main Authors: David C. Turner (Author), Russ Wada (Author), Helen Zhou (Author), Xiaowei Wang (Author), Rik deGreef (Author), Chandni Valiathan (Author), Lindsey Zhang (Author), Nancy Zhang (Author), Mita Kuchimanchi (Author), Tai‐Tsang Chen (Author), Marc Ballas (Author), Sandra A. G. Visser (Author)
• Format: Book
• Published: Wiley, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Single‐arm cohorts/trials are often used in early phase oncology programs to support preliminary clinical activity assessments for investigational products, administered alone or in combination with standard of care (SOC) agents. Benchmarking clinical activity of those combinations against...