Mesenchymal Stromal Cells from Osteoarthritic Synovium Are a Distinct Population Compared to Their Bone-Marrow Counterparts regarding Surface Marker Distribution and Immunomodulation of Allogeneic CD4+ T-Cell Cultures

• Главные авторы: Sebastien Hagmann (Автор), Claudia Rimmele (Автор), Florin Bucur (Автор), Thomas Dreher (Автор), Felix Zeifang (Автор), Babak Moradi (Автор), Tobias Gotterbarm (Автор)
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• Опубликовано: Hindawi Limited, 2016-01-01T00:00:00Z.
• Предметы: article
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Introduction. The participation of an inflammatory joint milieu has been described in osteoarthritis (OA) pathogenesis. Mesenchymal stromal cells (MSCs) play an important role in modulating inflammatory processes. Based on previous studies in an allogeneic T-cell coculture model, we aimed at further...