Development of highly organized lymphoid structures in Buruli ulcer lesions after treatment with rifampicin and streptomycin.

• Main Authors: Daniela Schütte (Author), Alphonse Um-Boock (Author), Ernestina Mensah-Quainoo (Author), Peter Itin (Author), Peter Schmid (Author), Gerd Pluschke (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2007-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Buruli ulcer caused by Mycobacterium ulcerans is an infection of the subcutaneous tissue leading to chronic necrotising skin ulcers. The pathogenesis is associated with the cytocidal and immunosuppressive activities of a macrolide toxin. Histopathological hallmark of progressing disease...