Design and Characterization of a Novel Venetoclax-Zanubrutinib Nano-Combination for Enhancing Leukemic Cell Uptake and Long-Acting Plasma Exposure
Leukemia remains incurable partly due to difficulties in reaching and maintaining therapeutic drug concentrations in the target tissues and cells. Next-generation drugs targeted to multiple cell checkpoints, including the orally active venetoclax (Bcl-2 target) and zanubrutinib (BTK target), are eff...
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Main Authors: | James Griffin (Author), Yan Wu (Author), Qingxin Mu (Author), Xinyan Li (Author), Rodney J. Y. Ho (Author) |
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Format: | Book |
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MDPI AG,
2023-03-01T00:00:00Z.
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