FUT8 upregulates CD36 and its core fucosylation to accelerate pericyte-myofibroblast transition through the mitochondrial-dependent apoptosis pathway during AKI-CKD

• Main Authors: Yaxi Shang (Author), Ziran Wang (Author), Fan Yang (Author), Weidong Wang (Author), Qingzhu Tang (Author), Xianan Guo (Author), Xiangning Du (Author), Xu Zhang (Author), Jiaojiao Hao (Author), Hongli Lin (Author)
• Format: Book
• Published: BMC, 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Activation of pericytes leads to renal interstitial fibrosis, but the regulatory mechanism of pericytes in the progression from AKI to CKD remains poorly understood. CD36 activation plays a role in the progression of CKD. However, the significance of CD36 during AKI-CKD, especial...