Combined Administration of (<i>R</i>)-Ketamine and the mGlu2/3 Receptor Antagonist LY341495 Induces Rapid and Sustained Effects in the CUMS Model of Depression via a TrkB/BDNF-Dependent Mechanism
Ketamine is an effective, rapid-acting antidepressant drug (RAAD), but it induces side effects. To overcome these challenges, attempts have been made to use safer enantiomer ((<i>R</i>)-ketamine) or mGlu2/3 receptor antagonists, which induce ketamine-like effects and enhance its action....
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| Main Authors: | , , |
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| Format: | Book |
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MDPI AG,
2022-01-01T00:00:00Z.
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