The Equipoise Between the Treatment of Glioblastoma and the Risk of Secondary Acute Myelogenous Leukemia: An Illustrative Case Report
We present a case report of a 56-year-old woman who was diagnosed with biopsy-proven left thalamic glioblastoma multiforme (GBM). She was treated with standard concurrent chemotherapy and radiation, as well as a 2-year period of adjuvant temozolomide. She relapsed 2 ½ years after starting her initia...
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| Format: | Book |
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SAGE Publishing,
2023-08-01T00:00:00Z.
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| 001 | doaj_d0f05dd8da904cfd827db3799e9f0a6d | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Moises Harari-Turquie MD |e author |
| 700 | 1 | 0 | |a Krishna Rekha Moturi MD |e author |
| 700 | 1 | 0 | |a Darrell D. Horton MD |e author |
| 700 | 1 | 0 | |a Ian Rabinowitz MD |e author |
| 245 | 0 | 0 | |a The Equipoise Between the Treatment of Glioblastoma and the Risk of Secondary Acute Myelogenous Leukemia: An Illustrative Case Report |
| 260 | |b SAGE Publishing, |c 2023-08-01T00:00:00Z. | ||
| 500 | |a 2324-7096 | ||
| 500 | |a 10.1177/23247096231193266 | ||
| 520 | |a We present a case report of a 56-year-old woman who was diagnosed with biopsy-proven left thalamic glioblastoma multiforme (GBM). She was treated with standard concurrent chemotherapy and radiation, as well as a 2-year period of adjuvant temozolomide. She relapsed 2 ½ years after starting her initial therapy and was treated with bevacizumab and lomustine, but she relapsed. She was then placed on a phase 1/2 clinical trial that included KHK2455 and mogamulizumab-kpkc individually and in combination for almost 4 years. She had a rapid demise due to the development of a neutropenic pneumonia and treatment-induced acute myeloid leukemia (AML) and elected for hospice care. | ||
| 546 | |a EN | ||
| 690 | |a Medicine (General) | ||
| 690 | |a R5-920 | ||
| 690 | |a Pathology | ||
| 690 | |a RB1-214 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Journal of Investigative Medicine High Impact Case Reports, Vol 11 (2023) | |
| 787 | 0 | |n https://doi.org/10.1177/23247096231193266 | |
| 787 | 0 | |n https://doaj.org/toc/2324-7096 | |
| 856 | 4 | 1 | |u https://doaj.org/article/d0f05dd8da904cfd827db3799e9f0a6d |z Connect to this object online. |