Potentiated Hsp104 variants suppress toxicity of diverse neurodegenerative disease-linked proteins
Protein misfolding is implicated in numerous lethal neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS) and Parkinson disease (PD). There are no therapies that reverse these protein-misfolding events. We aim to apply Hsp104, a hexameric AAA+ protein from yeast, to target misfo...
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| Main Authors: | , |
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| Format: | Book |
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The Company of Biologists,
2014-10-01T00:00:00Z.
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