TNFα Induces DNA and Histone Hypomethylation and Pulmonary Artery Smooth Muscle Cell Proliferation Partly via Excessive Superoxide Formation
<b>Objective:</b> The level of tumor necrosis factor-α (TNF-α) is upregulated during the development of pulmonary vascular remodeling and pulmonary hypertension. A hallmark of pulmonary arterial (PA) remodeling is the excessive proliferation of PA smooth muscle cells (PASMCs). The purpos...
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Main Authors: | Patrick Crosswhite (Author), Zhongjie Sun (Author) |
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Format: | Book |
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MDPI AG,
2024-05-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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