Hallmarks of Anaplastic Lymphoma Kinase Inhibitors with Its Quick Emergence of Drug Resistance

• Main Authors: Yong-Fu Qiu (Author), Lian-Hua Song (Author), Gang-Long Jiang (Author), Zhen Zhang (Author), Xu-Yan Liu (Author), Guan Wang (Author)
• Format: Book
• Published: Georg Thieme Verlag KG, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Anaplastic lymphoma kinase (ALK) is one of the most popular targets for anticancer therapies. In the past decade, the use of anaplastic lymphoma tyrosine kinase inhibitors (ALK-TKIs), including crizotinib and ceritinib, has been a reliable and standard options for patients with lung cancer,...