The effect of different intensity circuit resistance training on gremlin-1, Macrophage migration inhibitory factor and some cardiovascular risk factors in obese men

• Main Authors: Mohammad Karami (Author), Asieh Abbassi Daloii (Author), Ayoub Saeidi (Author)
• Format: Book
• Published: Shahid Beheshti University, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 2676-3710; 2645-4041; 10.52547/joeppa.15.3.1
• Keywords: circuit resistance training; obesity; macrophage migration inhibitory factor; gremlin-1; lipid profile; Sports medicine; RC1200-1245
• Source: فیزیولوژی ورزش و فعالیت بدنی, Vol 15, Iss 3, Pp 1-10 (2022)

Background and Purpose: More Adipose tissue is associated with the increase of inflammatory markers in obesity. This study aimed to evaluate the effect of different intensity circuit resistance training on gremlin-1, Macrophage migration inhibitory factor and some cardiovascular risk factors in obese men.Materials and Methods: In a semi-experimental trial, 44 obese men were selected and randomly divided into four groups including control (n=11), low intensity circuit resistance training (n=11), moderate intensity circuit resistance training (n=11) and high-intensity circuit resistance training (n=11) groups. Resistance training was performed in different intensities included 1) High-intensity circuit resistance training (80% 1RM) 2) Moderate intensity circuit resistance (60% 1RM) and 3) Low intensity circuit resistance training (40% 1RM), three sessions per week for 12 weeks. Serum levels of gremlin-1, MIFand Lipid profile (cholesterol, triglyceride, LDL and HDL) were measured using kit and ELISA method. Data were analyzed with Analysis of variance with repeated measures, dependent t-test and Bonferroni post hoc test at the P < 0.05.Results:12 weeks of circular resistance training with low, moderate and high intensity caused a significant decrease in gremlin-1 and MIF levels, significant decrease in cholesterol, triglyceride and LDL-c levels and significant increase in HDL-c levels (P = 0.001).Conclusion: It seems that circular resistance training with different intensities and especially high intensity can be an effective factor in counteracting the increase in observation of cardiovascular risk factors in obese people.