Airway Thiol-NO Adducts as Determinants of Exhaled NO

• Main Authors: Megan Pophal (Author), Zachary W. Grimmett (Author), Clara Chu (Author), Seunghee Margevicius (Author), Thomas Raffay (Author), Kristie Ross (Author), Anjum Jafri (Author), Olivia Giddings (Author), Jonathan S. Stamler (Author), Benjamin Gaston (Author), James D. Reynolds (Author)
• Format: Book
• Published: MDPI AG, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Thiol-NO adducts such as <i>S</i>-nitrosoglutathione (GSNO) are endogenous bronchodilators in human airways. Decreased airway <i>S</i>-nitrosothiol concentrations are associated with asthma. Nitric oxide (NO), a breakdown product of GSNO, is measured in exhaled breath as a bi...