Cover Image

Topical Sustained Delivery of Miltefosine Via Drug-Eluting Contact Lenses to Treat Acanthamoeba Keratitis

This study aimed to develop a miltefosine-eluting contact lens (MLF-CL) device that would allow sustained and localized miltefosine release for the treatment of Acanthamoeba keratitis. MLF-CLs were produced in three different miltefosine doses by solvent-casting a thin miltefosine-polymer film aroun...

Full description

Saved in:

Bibliographic Details
Main Authors:	Lin Chen (Author), Liangju Kuang (Author), Amy E. Ross (Author), Wissam Farhat (Author), Nikolay Boychev (Author), Sina Sharfi (Author), Levi N. Kanu (Author), Longqian Liu (Author), Daniel S. Kohane (Author), Joseph B. Ciolino (Author)
Format:	Book
Published:	MDPI AG, 2022-12-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Acanthamoeba keratitis in noncompliant soft contact lenses users: Genotyping and risk factors, a study from Cairo, Egypt
by: Eman E. Taher, et al.
Published: (2018)

Contact Lens-Associated Acanthamoeba Keratitis in Iran
by: AH Maghsood, et al.
Published: (2005)

Contact Lens-Associated Acanthamoeba Keratitis in Iran
by: AH Maghsood, et al.
Published: (2005)

Diagnosis and Treatment of Acanthamoeba Keratitis
by: Lincoln Lavado Landeo
Published: (2015)

Chitosan nanoparticles improve the effectivity of miltefosine against Acanthamoeba.
by: Alireza Latifi, et al.
Published: (2024)

Melatonin-Eluting Contact Lenses Effect on Tear Volume: In Vitro and In Vivo Experiments
by: María Serramito, et al.
Published: (2022)

Recent Applications of Contact Lenses for Bacterial Corneal Keratitis Therapeutics: A Review
by: Linyan Nie, et al.
Published: (2022)

The global epidemiology and clinical diagnosis of Acanthamoeba keratitis
by: Yuheng Zhang, et al.
Published: (2023)

Atorvastatin-Eluting Contact Lenses: Effects of Molecular Imprinting and Sterilization on Drug Loading and Release
by: Ana F. Pereira-, et al.
Published: (2021)

The role of naturally acquired intracellular Pseudomonas aeruginosa in the development of Acanthamoeba keratitis in an animal model.
by: Binod Rayamajhee, et al.
Published: (2024)

Molecular Characterization and Sequencing of a Gene Encoding Mannose Binding Protein in an Iranian Isolate of Acanthamoeba castellanii as a Major Agent of Acanthamoeba Keratitis
by: SH Farnia, et al.
Published: (2008)

Molecular Characterization and Sequencing of a Gene Encoding Mannose Binding Protein in an Iranian Isolate of Acanthamoeba castellanii as a Major Agent of Acanthamoeba keratitis
by: M Niyyati, et al.
Published: (2008)

First report of multiple mixed-subgenotype infections of Acanthamoeba spp. from clinical isolates of human keratitis cases in Japan
by: M.M. Rahman, et al.
Published: (2014)

The Role of Biofilms in Contact Lens Associated Fungal Keratitis
by: Jipan Yi, et al.
Published: (2023)

Knowledge and attitude of youth towards contact lenses in Karachi, Pakistan
by: Rafia Irfan, et al.
Published: (2019)

Resveratrol-Loaded Hydrogel Contact Lenses with Antioxidant and Antibiofilm Performance
by: María Vivero-Lopez, et al.
Published: (2021)

Improvements in Topical Ocular Drug Delivery Systems: Hydrogels and Contact Lenses
by: Andreza Maria Ribeiro, et al.
Published: (2015)

Enhanced drug loading efficiency of contact lenses via salt-induced modulation
by: Qiang Zhu, et al.
Published: (2019)

Effects of Scleral Contact Lenses for Keratoconus Management on Visual Quality and Intraocular Pressure
by: Formisano M, et al.
Published: (2021)

Use and misuse of cosmetic contact lenses among US adolescents in Southeast Texas
by: Berenson AB, et al.
Published: (2019)

Thermally-Responsive Loading and Release of Elastin-Like Polypeptides from Contact Lenses
by: Wan Wang, et al.
Published: (2019)

Effect of Silicone Hydrogel Contact Lenses on Stability of Cellular and Intracellular Membranes in Corneal Epithelium
by: T.A. Veliksar, et al.
Published: (2017)

Extended levobunolol release from Eudragit nanoparticle-laden contact lenses for glaucoma therapy
by: Navneet Kumar, et al.
Published: (2020)

Keratitis
Published: (2012)

Long-term follow-up of school-age children on the effectiveness of myopia correction with contact lenses
by: Nataliia Aleieva, et al.
Published: (2021)

Inkjet drug printing onto contact lenses: Deposition optimisation and non-destructive dose verification
by: Thomas D. Pollard, et al.
Published: (2023)

Biocompatibility and Comfort during Extended Wear of Mel4 Peptide-Coated Antimicrobial Contact Lenses
by: Parthasarathi Kalaiselvan, et al.
Published: (2022)

Controllable release of pirfenidone by polyvinyl alcohol film embedded soft contact lenses in vitro and in vivo
by: Caiqing Wu, et al.
Published: (2021)

Effect of a Cationic Surfactant on Microemulsion Globules and Drug Release from Hydrogel Contact Lenses
by: Cesar Torres-Luna, et al.
Published: (2019)

Miltefosine enhances infectivity of a miltefosine-resistant Leishmania infantum strain by attenuating its innate immune recognition.
by: Dimitri Bulté, et al.
Published: (2021)

Contact lenses as a preferred choice for vision correction in various clinical scenarios with regard to work environment
by: Agnieszka Byś, et al.
Published: (2024)

Controlled Release of rAAV Vectors from APMA-Functionalized Contact Lenses for Corneal Gene Therapy
by: Fernando Alvarez-Rivera, et al.
Published: (2020)

Successful treatment of multifocal cutaneous leishmaniasis with miltefosine
by: Bhushan Madke, et al.
Published: (2011)

Availability of miltefosine for the treatment of kala-azar in India
by: Shyam Sundar, et al.
Published: (2005)

Enhancement of capsular hypermucoviscosity in Klebsiella pneumoniae by Acanthamoeba.
by: Jian-Ming Huang, et al.
Published: (2023)

Galactose as novel target against Acanthamoeba cysts.
by: Ayaz Anwar, et al.
Published: (2019)

Occurrence of Acanthamoeba in hospitals: a literature review
by: Danielly Joani Bullé, et al.
Published: (2020)

Efficacy and Safety of AmBisome in Combination with Sodium Stibogluconate or Miltefosine and Miltefosine Monotherapy for African Visceral Leishmaniasis: Phase II Randomized Trial.
by: Monique Wasunna, et al.
Published: (2016)

Novel daily disposable therapeutic contact lenses based on chitosan and regenerated silk fibroin for the ophthalmic delivery of diclofenac sodium
by: Rachasit Jeencham, et al.
Published: (2020)

EPIDEMIOLOGY LENSES : A PRESENTATION
by: Prakash V. Kotecha
Published: (2010)