Intramedullary craniovertebral junction tuberculoma: An uncommon location of a common disease

Summary: Central nervous system involvement is observed in no more than 10% of patients with systemic tuberculosis. Although CNS tuberculosis is not rare in endemic countries, such as India, intramedullary tuberculosis is not commonly reported. In this study, we report a case of a 40-year-old female...

Full description

Saved in:
Bibliographic Details
Main Authors: Rajendra S. Jain (Author), Rahul Handa (Author), Trilochan Srivastava (Author), Swayam Prakash (Author), Kadam Nagpal (Author), Indu Bhana (Author), Pankaj K. Gupta (Author)
Format: Book
Published: Elsevier, 2014-07-01T00:00:00Z.
Subjects:
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Summary: Central nervous system involvement is observed in no more than 10% of patients with systemic tuberculosis. Although CNS tuberculosis is not rare in endemic countries, such as India, intramedullary tuberculosis is not commonly reported. In this study, we report a case of a 40-year-old female who presented with a six-year history of insidious onset, gradually progressive, asymmetric quadriparesis. She was diagnosed with intramedullary tuberculoma at the craniovertebral junction and showed significant clinico-radiological improvement with medical management alone. To the best of our knowledge, this report describes the first case of intramedullary tuberculoma at the craniovertebral junction to be reported. With the increased availability of MRI in developing countries, it is now possible for clinicians to diagnose this condition without performing a biopsy. It is important for the clinicians in developed countries to be highly suspicious of intramedullary tuberculoma, as there has been a resurgence of CNS tuberculosis due to the emergence of the HIV pandemic. Keywords: Intramedullary, Tuberculoma, Craniovertebral junction
Item Description:1876-0341
10.1016/j.jiph.2014.04.006