A Lentiviral Vector Expressing Japanese Encephalitis Virus-like Particles Elicits Broad Neutralizing Antibody Response in Pigs.

• Main Authors: Mélissanne de Wispelaere (Author), Meret Ricklin (Author), Philippe Souque (Author), Marie-Pascale Frenkiel (Author), Sylvie Paulous (Author), Obdulio Garcìa-Nicolàs (Author), Artur Summerfield (Author), Pierre Charneau (Author), Philippe Desprès (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Japanese encephalitis virus (JEV) is the major cause of viral encephalitis in Southeast Asia. Vaccination of domestic pigs has been suggested as a "one health" strategy to reduce viral disease transmission to humans. The efficiency of two lentiviral TRIP/JEV vectors expressing t...