Cyclophosphamide induces ovarian granulosa cell ferroptosis via a mechanism associated with HO-1 and ROS-mediated mitochondrial dysfunction
Abstract Abnormal granulosa cell (GC) death contributes to cyclophosphamide (CTX) induced primary ovarian insufficiency (POI). To investigate the contribution of GCs to POI, gene profiles of GCs exposed to CTX were assessed using RNA-Seq and bioinformatics analysis. The results showed the differenti...
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| Main Authors: | , , , , , , , |
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| Format: | Book |
| Published: |
BMC,
2024-05-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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