Adipose-Derived Mesenchymal Stem Cells Inhibit JNK-Mediated Mitochondrial Retrograde Pathway to Alleviate Acetaminophen-Induced Liver Injury
Acetaminophen (APAP) is the major cause of drug-induced liver injury, with limited treatment options. APAP overdose invokes excessive oxidative stress that triggers mitochondria-to-nucleus retrograde pathways, contributing to APAP-induced liver injury (AILI). Mesenchymal stem cell therapy is a promi...
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Main Authors: | Yelei Cen (Author), Guohua Lou (Author), Jinjin Qi (Author), Minwei Li (Author), Min Zheng (Author), Yanning Liu (Author) |
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Format: | Book |
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MDPI AG,
2023-01-01T00:00:00Z.
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