Preventing muscle wasting by osteoporosis drug alendronate in vitro and in myopathy models via sirtuin‐3 down‐regulation

• Main Authors: Hsien‐Chun Chiu (Author), Chen‐Yuan Chiu (Author), Rong‐Sen Yang (Author), Ding‐Cheng Chan (Author), Shing‐Hwa Liu (Author), Chih‐Kang Chiang (Author)
• Format: Book
• Published: Wiley, 2018-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background A global consensus on the loss of skeletal muscle mass and function in humans refers as sarcopenia and cachexia including diabetes, obesity, renal failure, and osteoporosis. Despite a current improvement of sarcopenia or cachexia with exercise training and supportive therapies, a...