A Case of Follicular Tumor of Uncertain Malignant Potential (FT-UMP) with Glomeruloid Features Showing Capsular Mucinous Degeneration

The most recent revision of the World Health Organization (WHO) Classification of Tumours of Endocrine Organs introduced a new variant of follicular thyroid carcinoma (FTC). It is characterized by a "glomeruloid" architectural pattern of growth. We present a case of follicular tumor with g...

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Main Authors: Daniela Cabibi (Author), Andrea Mondello (Author), Ada Maria Florena (Author), Giulia Rimi (Author), Antonino Giulio Giannone (Author), Calogero Cipolla (Author), Maria Rosaria Valerio (Author), Giuseppa Graceffa (Author)
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Published: Hindawi Limited, 2021-01-01T00:00:00Z.
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100 1 0 |a Daniela Cabibi  |e author 
700 1 0 |a Andrea Mondello  |e author 
700 1 0 |a Ada Maria Florena  |e author 
700 1 0 |a Giulia Rimi  |e author 
700 1 0 |a Antonino Giulio Giannone  |e author 
700 1 0 |a Calogero Cipolla  |e author 
700 1 0 |a Maria Rosaria Valerio  |e author 
700 1 0 |a Giuseppa Graceffa  |e author 
245 0 0 |a A Case of Follicular Tumor of Uncertain Malignant Potential (FT-UMP) with Glomeruloid Features Showing Capsular Mucinous Degeneration 
260 |b Hindawi Limited,   |c 2021-01-01T00:00:00Z. 
500 |a 2090-6781 
500 |a 2090-679X 
500 |a 10.1155/2021/1686025 
520 |a The most recent revision of the World Health Organization (WHO) Classification of Tumours of Endocrine Organs introduced a new variant of follicular thyroid carcinoma (FTC). It is characterized by a "glomeruloid" architectural pattern of growth. We present a case of follicular tumor with glomeruloid features, with Alcian Blue positive mucinous stromal degeneration in foci of questionable capsular microinvasion. At our knowledge, this the second case of glomeruloid follicular tumor in the literature and the first case in which Alcian Blue staining was used to investigate capsular invasion. Moreover, RAS mutation further supports that this is a variant of follicular tumor with uncertain malignant potential. 
546 |a EN 
690 |a Pathology 
690 |a RB1-214 
655 7 |a article  |2 local 
786 0 |n Case Reports in Pathology, Vol 2021 (2021) 
787 0 |n http://dx.doi.org/10.1155/2021/1686025 
787 0 |n https://doaj.org/toc/2090-6781 
787 0 |n https://doaj.org/toc/2090-679X 
856 4 1 |u https://doaj.org/article/d29c55261f1e4d21933e9cc12a258c7a  |z Connect to this object online.