Antibacterials in Aquatic Environment and Their Toxicity to Fish

Antibacterial agents are commonly present in aquatic environment at low concentrations. Terrestrial animal farms, human medicine and aquaculture are main sources of water contamination with antibacterials. Antibiotics were proved to be directly toxic to fish causing oxidative stress, general stress...

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Bibliographic Details
Main Authors: Bartosz Bojarski (Author), Barbara Kot (Author), Małgorzata Witeska (Author)
Format: Book
Published: MDPI AG, 2020-08-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Bartosz Bojarski  |e author 
700 1 0 |a Barbara Kot  |e author 
700 1 0 |a Małgorzata Witeska  |e author 
245 0 0 |a Antibacterials in Aquatic Environment and Their Toxicity to Fish 
260 |b MDPI AG,   |c 2020-08-01T00:00:00Z. 
500 |a 10.3390/ph13080189 
500 |a 1424-8247 
520 |a Antibacterial agents are commonly present in aquatic environment at low concentrations. Terrestrial animal farms, human medicine and aquaculture are main sources of water contamination with antibacterials. Antibiotics were proved to be directly toxic to fish causing oxidative stress, general stress response, histopathological lesions, hematological, metabolic, and reproductive disorders, as well as immunosuppressive and genotoxic effects. Environmentally realistic low concentrations of antibiotics also disturb aquatic bacterial communities causing alterations in fish symbiotic microbiota and induce emergence of antibiotic-resistant pathogenic bacteria by exerting selective pressure on spread of antibiotic-resistance genes. 
546 |a EN 
690 |a antibiotics 
690 |a chemotherapeutics 
690 |a toxic effects 
690 |a oxidative stress 
690 |a hematological changes 
690 |a histopathology 
690 |a Medicine 
690 |a R 
690 |a Pharmacy and materia medica 
690 |a RS1-441 
655 7 |a article  |2 local 
786 0 |n Pharmaceuticals, Vol 13, Iss 8, p 189 (2020) 
787 0 |n https://www.mdpi.com/1424-8247/13/8/189 
787 0 |n https://doaj.org/toc/1424-8247 
856 4 1 |u https://doaj.org/article/d2d79a49d04c4e75b8f04339fa68d5b0  |z Connect to this object online.