The Influence of Short Motifs on the Anticancer Activity of HB43 Peptide

• Main Authors: Claudia Herrera-León (Author), Francisco Ramos-Martín (Author), Hassan El Btaouri (Author), Viviane Antonietti (Author), Pascal Sonnet (Author), Laurent Martiny (Author), Fabrizia Zevolini (Author), Chiara Falciani (Author), Catherine Sarazin (Author), Nicola D'Amelio (Author)
• Format: Book
• Published: MDPI AG, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Despite the remarkable similarity in amino acid composition, many anticancer peptides (ACPs) display significant differences in terms of activity. This strongly suggests that particular relative dispositions of amino acids (motifs) play a role in the interaction with their biological target, which i...