FoxK1 associated gene regulatory network in hepatic insulin action and its relationship to FoxO1 and insulin receptor mediated transcriptional regulation

• Main Authors: Prasanna K.R. Allu (Author), Maria Dafne Cardamone (Author), Antonio S. Gomes (Author), Alessandra Dall'agnese (Author), Carly Cederquist (Author), Hui Pan (Author), Jonathan M. Dreyfuss (Author), Sven Enerbäck (Author), C. Ronald Kahn (Author)
• Format: Book
• Published: Elsevier, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Insulin acts on the liver via changes in gene expression to maintain glucose and lipid homeostasis. This study aimed to the Forkhead box protein K1 (FOXK1) associated gene regulatory network as a transcriptional regulator of hepatic insulin action and to determine its role versus FoxO1 an...