Successful use of ofatumumab in two cases of early-onset juvenile SLE with thrombocytopenia caused by a mutation in protein kinase C δ
Abstract Background We previously described an endogamous Pakistani kindred in whom we identified a novel homozygous missense mutation in the PRKCD gene encoding for protein kinase C δ (PKCδ) as a cause of monogenic systemic lupus erythematosus (SLE). PKCδ has a role in the negative regulation of B...
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| Main Authors: | , , , , , , |
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| Format: | Book |
| Published: |
BMC,
2018-09-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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